Ginkgo Biloba Recommended Dosage

Ginkgo Biloba Recommended Dosage

The beneficial effects of ginkgo biloba are considered dose-dependent and you should carefully stick to the recommended dosage to avoid side effects. Dose-dependent benefits of ginkgo biloba have been reported in cognitive impairment, hypoxia, aging, tinnitus, cerebrovascular insufficiency and many other disorders. Ginkgo biloba should not be given to children (Diamond and Mondragon, 2017).

The following different recommended dosage for the treatment of different disorders have been reported.

  1. Dosage for Cerebral vascular insufficiency: The German Commission E recommends 120-240 mg/day ginkgo biloba extract in two to three divided doses.
  2. Dosage for schizophrenia: the leaf extract 761 of 120-360 mg/day has bend used recommended for 8 weeks (Diamond and Mondragon, 2017).
  3. Dosage for dementia, memory and circulatory disorders: Doses recommended 60-460 mg/day ginkgo biloba extract in two to three divided doses for up to one year. Improvement of one or more measures has been associated with doses ranging from 120 to 300 mg/day for 3-13 weeks (Herrschaft et al., 2012).
  4. Dosage for anxiety: Ginkgo biloba leaf extract called EGb 761 has been taken from 60 to 180 mg three times per day for 4 weeks.
  5. Dosage for vertigo and dizziness: The leaf extract called EGb 761 of 160 mg has been recommended once in a day or divided into two doses for 3 months.
  6. Dosage for Tardive dyskinesia: also called a movement disorder can be treated by taking 80 mg of ginkgo biloba leaf extract three times a day for 12 weeks.
  7. Dosage for multicenter double blind: Randomize placebo-controlled trial involving 410 outpatients with mild to moderate dementia, a single dose of 240 mg of EGb 761 for 24 weeks was safe showing a significant advantage over placebo for apathy or indifferent, sleep and behavior.
  8. Dosage for premenstrual syndrome: Ginkgo biloba extract called EGb 761 of 160 mg has been recommended twice a day from the sixteenth day of the menstrual cycle up to the fifth day of the next cycle (Dante and Facchinetti, 2011).
  9. Dosage for vision loss: Ginkgo biloba leaf extract of 120 to 160 mg has been recommended in two or three doses per day for 1 year.
  10. Dosage for memory problems and Alzheimer’s disease: Many studies have used 120–240 mg daily in divided doses, standardized to contain 24–32% flavone glycosides (flavonoids or heterosides) and 6–12% triterpene lactones (terpenoids) (Yang et al., 2016).
  11. Intermittent claudication: Studies have used 120–240 mg of ginkgo biloba leaf extract divided in 2 to 3 doses per day.

Overall studies indicated that 4-6 weeks are needed for positive effects on memory, mood or physiological function with studies of 4-52 weeks (80-720 mg/day). Doses between 120 and 240 mg take two or three times per day are considered optimal in most cases for cognitive and cardiovascular disorders. Experts suggest starting at a low dose of 120 mg per day and then increasing gradually (Diamondand Bailley, 2013). Always get advice from your doctor or physician for an acceptable dosage to avoid the negative effects of overdosage.

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References

Dante, G., & Facchinetti, F. (2011). Herbal treatments for alleviating premenstrual symptoms: a systematic review. Journal of Psychosomatic Obstetrics & Gynecology, 32(1), 42-51.

Diamond, B. J., & Bailey, M. R. (2013). Ginkgo biloba: indications, mechanisms, and safety. Psychiatric Clinics, 36(1), 73-83.

Diamond, B. J., & Mondragon, A. (2017). Ginkgo biloba. Complementary and Integrative Treatments in Psychiatric Practice. Washington: American Psychiatric Association Publishing, 149.

Herrschaft, H., Nacu, A., Likhachev, S., Sholomov, I., Hoerr, R., & Schlaefke, S. (2012). Ginkgo biloba extract EGb 761® in dementia with neuropsychiatric features: a randomised, placebo-controlled trial to confirm the efficacy and safety of a daily dose of 240 mg. Journal of Psychiatric Research, 46(6), 716-723.

Yang, G., Wang, Y., Sun, J., Zhang, K., & Liu, J. (2016). Ginkgo biloba for mild cognitive impairment and alzheimer’s disease: a systematic review and meta-analysis of randomized controlled trials. Current topics in medicinal chemistry, 16(5), 520-528.